Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CREBBP All Species: 29.09
Human Site: S164 Identified Species: 53.33
UniProt: Q92793 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92793 NP_001073315.1 2442 265351 S164 K Q V G L A T S S P A T S Q T
Chimpanzee Pan troglodytes XP_523285 2442 265358 S164 K Q V G L A T S S P A T S Q T
Rhesus Macaque Macaca mulatta XP_001095225 2442 265320 S164 K Q V G L A T S S P A T S Q T
Dog Lupus familis XP_851777 2404 260682 S164 K Q V G L V T S S P A T S Q T
Cat Felis silvestris
Mouse Mus musculus P45481 2441 265456 S163 K Q V G L V T S S P A T S Q T
Rat Rattus norvegicus NP_596872 2444 265618 S163 K Q V G L V T S S P A T S Q T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414964 2447 266615 S150 K Q V G M V T S S P A T S Q T
Frog Xenopus laevis NP_001088637 2428 264402 G157 K Q V S M V A G S P A A P Q A
Zebra Danio Brachydanio rerio NP_001082924 2111 234059 L86 R K L I Q Q Q L V L L L H A H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_524642 3276 340709 M254 P G G G G G G M I N S V S V P
Honey Bee Apis mellifera XP_001122031 2606 284119 S170 V S L G N L P S S I A S S L A
Nematode Worm Caenorhab. elegans P34545 2056 227161 F31 A L E S L E A F P T S S K D T
Sea Urchin Strong. purpuratus XP_782558 2635 288594 T234 M G Q F N P S T G A M P I N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.4 93.9 N.A. 94.8 95.8 N.A. N.A. 88 76 61.5 N.A. 36.5 42.7 30.5 38.5
Protein Similarity: 100 99.9 99.6 95.5 N.A. 96.4 97.2 N.A. N.A. 92 83.3 68.8 N.A. 46.7 54.7 43.9 50.9
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 86.6 46.6 0 N.A. 13.3 33.3 13.3 0
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 93.3 53.3 20 N.A. 20 46.6 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 24 16 0 0 8 70 8 0 8 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 16 8 70 8 8 8 8 8 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % H
% Ile: 0 0 0 8 0 0 0 0 8 8 0 0 8 0 0 % I
% Lys: 62 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 0 8 16 0 54 8 0 8 0 8 8 8 0 8 0 % L
% Met: 8 0 0 0 16 0 0 8 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 16 0 0 0 0 8 0 0 0 8 0 % N
% Pro: 8 0 0 0 0 8 8 0 8 62 0 8 8 0 8 % P
% Gln: 0 62 8 0 8 8 8 0 0 0 0 0 0 62 0 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 0 16 0 0 8 62 70 0 16 16 70 0 8 % S
% Thr: 0 0 0 0 0 0 54 8 0 8 0 54 0 0 62 % T
% Val: 8 0 62 0 0 39 0 0 8 0 0 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _